The following post is by guest author Adrian Arrieta, M.S., B.S. Adrian is a graduate student and doctoral candidate in the San Diego State University (SDSU) and UC San Diego Joint Cell and Molecular Biology Doctoral Program, in the lab of Dr. Chris Glembotski. Adrian’s research focus is on endoplasmic reticulum (ER) stress pathways during…
Journal Club: Adaptation Within Embryonic and Neonatal Heart Environment Reveals Alternative Fates for Adult c-Kit+ Cardiac Interstitial Cells
Bingyan (Jessica) Wang received her PhD degree in December 2019 from the Joint-Doctoral program at UC San Diego and San Diego State University, under the supervision of Dr. Mark Sussman. She previously earned an MS in Biological Sciences from CSULA, as well as an MS in Biochemical Engineering from TU Delft in the Netherlands. Jessica’s…
Beyond the Bench: Insights from an Editor with Rong Tian, MD, PhD
Editor’s Note: “Beyond the Bench” is a recurring interview series featuring discussions with both early-career and established investigators, highlighting the people and the ideas behind the latest discoveries in cardiovascular research. For comments or suggestions, please contact either Ron Vagnozzi (ronald.vagnozzi@cchmc.org) or Kim Ho (klho@ualberta.ca) For this special edition of “Beyond the Bench”, we are…
Technical Section: Methods for Detecting Protein-lncRNA Interaction and lncRNA-Chromatin Interaction
Among the many proteins encoded by the eukaryotic genome, a considerable number of them interact with RNA molecules to exert their function. These proteins are collectively termed RNA binding proteins (RBPs), and emerging evidence has shown that they play important roles in physiological and diseased conditions of the cardiovascular system [1, 2]. Notably, hundreds of…
Women in Science – Challenges and Solutions
“Women in Science – Challenges and Solutions” is a recurring interview series with both early-career and established investigators, highlighting the women perspective about science and beyond. Author: Litsa Kranias, PhD “If you love doing research and you are passionate about it, you will be successful. Everything will fall in place and it will be a…
Journal Club – The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function
Interview with Christopher N. Johnson, Ph.D. What inspired you to become a scientist? As a child I was fascinated by science fiction movies such as Bill and Ted’s Excellent Adventure, and Back to the Future. During those years I started to seriously wonder what was physically possible, and what are the limits of science. As…
Journal Club- MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress
My name is Jonathan Lambert and I am currently a post-doctoral fellow in the lab of Dr. Luca Scorrano at the University of Padua in Italy. I grew up in Atlanta, GA and earned a B.S. in Biology from Boston College in 2011. My research career started as a technician in Dr. John Calvert’s lab…
Beyond the Bench: A Retrospective by Dr. Shirin Doroudgar
Editor’s Note: “Beyond the Bench” is a recurring interview series featuring discussions with both early-career and established investigators, highlighting the people and the ideas behind the latest discoveries in cardiovascular research. For comments or suggestions, please contact either Ron Vagnozzi (ronald.vagnozzi@cchmc.org) or Kim Ho (klho@ualberta.ca) As scientists we are charged with being analytical, methodical, and…
ACADEMIA: To be or not to be
This post features experiences shared by those who chose to pursue a career in academia. Our follow up post in this section will include experiences from those who chose to continue their careers on the academic track. By Rushita Bagchi and Marina Felisbino Kristine Y. DeLeon-Pennell, PhD Assistant Professor, Medical University of South Carolina…
Technical Section – Super Resolution Microscopy
Fluorescence microscopy has been a key tool in biology, allowing us to characterize and obtain spatial information of structures and processes taking place in situ at the cellular/subcellular, tissue, and organism scales. Fluorescence microscopy works by shining lights of specific wavelengths that excite fluorophores, which in turn absorb and emit light that can be detected…
